Scientists map the genetic evolution of a type of T-ALL
The key genetic events responsible for initiating the early stages of a type of childhood leukaemia have been identified by scientists at The Institute of Cancer Research, London.
Scientists have tracked the branching pattern of evolution in a form of childhood leukaemia – and identified a ‘founder’ mutation that may be the trigger for development of the disease. They believe the findings could be used in the development of new targeted drugs.
Leukaemia develops when DNA faults – or ‘mutations’ – occur in maturing blood cells, triggering further genetic mutations that cause the cells to grow out of control.....
Read the full article at https://www.icr.ac.uk/news-archive/scientists-map-the-genetic-evolution-of-childhood-leukaemia